Monday, 29 June 2009

Tamiflu effective in treating flu in children with chronic conditions

This is an excellent article and a possible life saver. Make sure your
doctor read it as well.

Don't assume that doctors are uptodate with current medical practises.
Many just don't have time to read journals.

http://www.bcm.edu/news/item.cfm?newsID=1470

Tamiflu effective in treating flu in children with chronic conditions

RSS icon HOUSTON -- (June 29, 2009) -- Children with chronic health
conditions benefit from the flu-fighting drug oseltamivir (Tamiflu)
when doctors prescribe it quickly – as soon as they suspect the
youngster has influenza – said an expert at Baylor College of Medicine
in a study that appears in the journal Pediatrics.

"This study demonstrates that those individuals who have underlying
medical conditions and thereby are at greater risk from complications
from influenza benefit significantly from the use of Tamiflu early in
their disease process," said Dr. Pedro Piedra, professor of molecular
virology and microbiology and pediatrics at BCM, and lead author of
the study.
Confirmatory test

Using health-claims data from six influenza seasons, researchers found
that those children and adolescents between the ages of 1 and 17 who
were at high risk of influenza complications showed significant
reductions in the risks of respiratory illnesses other than pneumonia.
It also reduced the risk of otitis media (a middle ear infection) and
hospitalization within 14 days of the influenza diagnosis when
prescribed Tamiflu. Significant risk reductions were also apparent 30
days after the influenza diagnosis.

Piedra noted the importance of diagnosing the influenza virus using a
confirmatory test, which led to a higher likelihood of prescribing
Tamiflu.

"If you are not thinking about the flu, you are not thinking about how
to treat the flu," said Piedra.
Role in H1N1 treatment

He also noted the significance this will have with the current H1N1
(swine influenza) pandemic in which antiviral treatment is important.

"If we have a major wave in the fall months and the vaccines are not
yet available, antiviral treatments will be the only way we have to
either prevent or treat H1N1 (swine influenza)," said Piedra.

Others who contributed to this study include Kathy L. Schulman of
Thomson Reuters and Dr. William A. Blumentals of Roche. Funding for
this study came from Roche.

For more information on basic science research at Baylor College of
Medicine, please go to www.bcm.edu/fromthelab or www.bcm.edu/news.

Was this article helpful? We would like to hear from you.

Saturday, 27 June 2009

swine flu idiots! Why no flu deaths so far?

Swine flu had claimed 5 Australian deaths so far and yet none of them
are from normal flu.

How could Australian experts ever deem swine flu to be MILDER than
normal flu?

The difference in the deaths will determine the severity of Swine flu
over normal flu. If there are 10 swine flu deaths with only one normal
flu, it will mean that there will be 25,000 deaths due to Swine Flu
compared to 2,500 for normal flu.

Remember that some types of normal flu is already resistant to
Tamilflu but these are still rare, whereas swine flu is supposed to be
treatable with TAmilflu and yet it had caused 5 deaths in Australia
alone.

No details on the usage of Tamilfu but in Thailand and Chile, they had
used Tamilflu and yet patients still die.

What makes Swine flu dangerous is not its effects. It is much milder
than SARS but people take it so lightly that it will kill far more
than SARS just as normal flu is, expect that swine flu is many times
more lethal than normal flu, not milder. Australian so called experts
should wake up and study their facts clearly.

View of one sane Australian expert

An infectious disease specialist, not a doctor mind you, admit that
swine flu will kill more than normal flu because Australians don't
have immunity to it at all.

Even normal flu, we don't have immunity as well but we have vaccines
but they are given only to those who are in the highly risky groups of
younger than 2 and older than 60 and yet, many still died.

Never heard of any pregrant women dying from normal flu and no call
for them to be innoculated with flu vaccine.

I wonder what this expert believe that Swine flu is milder than Normal
flu!

http://www.abc.net.au/news/stories/2009/06/27/2610255.htm?section=australia


More swine flu deaths 'a certainty'

By Jennifer Macey for AM

AM | abc.net.au/am

Posted 11 hours 36 minutes ago
Updated 11 hours 7 minutes ago
Too late...'in the ideal world you would vaccinate several months
before the outbreak starts.'

Too late...'in the ideal world you would vaccinate several months
before the outbreak starts.' (AAP Image: Dave Hunt)

* Audio: Swine flu yet to peak in Australia (AM)
* Map: Sydney 2000
* Related Story: UK swine flu tally tops 4,300
* Related Story: Torres Strait confirms first swine flu case

An infectious disease expert says the swine flu vaccine will be
available too late to help many of the people who are going to
contract the virus.

Four people have died so far and in New South Wales, two children are
in intensive care because of the virus.

One of the children has no pre-existing medical conditions.

Professor of Infectious Diseases and Epidemiology at the University of
New South Wales, Raina Macintyre, told AM it is certain more people
will die from swine flu in Australia.

"We expect that it will peak towards the end of July or early August,"
she said.

"That's when we'll really be at the height of the epidemic, and we
would expect something of the same range or higher, but in the same
ball park of a bad flu season.

"It could be anywhere from 10 to 30 per cent of the Australian
population over the whole winter. Every year from seasonal flu there
are about 2,500 deaths from flu and pneumonia."

She says swine flu deaths are expected to be higher because people
have not built up immunity to the virus.

"Any influenza, even seasonal influenza, has a higher rate of
complications and death in people with pre-existing conditions because
they're just more vulnerable to infections like influenza," she said.

"So, it's not unexpected really that the first deaths that we're
seeing are in people who are immuno-compromised or have chronic
diseases."

Professor Macintyre says the vaccine for the flu expected to be
available by the end of July will not be soon enough.

"No, it's not ideal. Normally with seasonal flu we vaccinate people in
February or March, and the flu season starts in June and beyond," she
said.

"So, really, in the ideal world you would vaccinate several months
before the outbreak starts.

"In this case, we'll be vaccinating at the peak of the outbreak, so
half of the people who are going to be get infected will already be
infected and won't be able to benefit from the vaccine.

"But, it's still worth doing, because there's still all the other half
of the people who have not been infected that could receive protection
from the vaccine."

Tags: health, diseases-and-disorders, swine-influenza, australia, nsw,
sydney-2000

Deaths despite taking Tamilfu

Deaths in Chile and Thailand occurred while they are being given
Tamilflu.

Not sure if they took Tamilflu too late but either way it is worrying.

If taken too late, it will increase the chance of Swine Flu that is
immune to Tamilflu.

It it was taken on time, it shows that Swine Flu is already immune to
Tamilflu.

http://www.philstar.com/Article.aspx?articleId=481534&publicationSubCategoryId=200

Chile reports four new deaths due to A/H1N1 flu
Updated June 27, 2009 09:41 AM

SANTIAGO (Xinhua) -- The Chilean authorities confirmed on Friday four
new deaths due to A/H1N1 flu, raising the death toll in the country to
12.

The authorities said that two patients were from Nuble province, one
from Valdivia and one from Osorio.

The victims from Nuble, southern Chile, were a 48-year-old female
patient and a 47-year-old male, said the authorities.

The female patient was treated with anti-viral drug Oseltamivir from
June 15, but she was taken to the hospital due to complications on
June 19.

The male patient did not seek medical consultation on time. When he
went to the health center, he was hospitalized and received treatment.

Nuble's health official Ivan Paul Espinoza said that most of the cases
showed light symptoms.

The other death was a male patient of 41 years old from Valdivia, 800
km south to Santiago, the capital of Chile.

The seven-year-old girl in Osorio is the first one who did not have
symptoms and the first child who died in the country.

Thai expert: swine flu milder than normal flu which kills 30%!!

http://www.nationmultimedia.com/2009/06/27/national/national_30106194.php

Despite having 2 deaths due to Swine flu of apparently healthy
individuals, Thai Minister of Health deemed Swine Flu less dangerous
than normal flu because normal flu will kill 30% of patients.

Avian flu and Sars BOTH kill about 60%. Which flu kills about 30%?
Not even Spanish flu can kill 30%, only about 5%.

One self appointed expert in scm even deemed that normal flu routinely
kills people older than 2 and younger than 60.

I have yet to see any evidence of it yet.

TYPE-A (H1N1) VIRUS
Flu death toll rises to 2
By The Nation


A-40-year-old woman and a 42-year-old man in Bangkok have become the
country's first two fatalities linked to the type-A (H1N1) influenza
virus, Public Health Minister Witthaya Kaewparadai announced Saturday.
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Witthaya told a press conference that the woman fell ill on June 8 and
wa admitted to a private hospital seven days later with high fever and
pneumonia.

She was given oseltamivir anti-viral drug for five days but she her
condition worsened and she died on June 20.

The second victim fell ill on June 18 with fever and running nose.

He was admitted to a hospital on June 23 with high fever, coughing and
pneumonia.

He was also given oseltamivir anti-viral drug but his condition
worsened and he died on Friday.

Despite the deaths, Witthaya pleaded the public not to panic.

He said so far 1,209 type-A (H1N1) flu cases have been reported in
Thailand. Of these, 1,190 patients have been cured and 16 are still
inside hospitals.

He said 90 per cent of the cases recovered by themselves.

Witthaya said the type-A (H1N1) influenza has much lower fatality rate
than normal influenza which killed about 30 to 40 per cent of
patients.

Friday, 26 June 2009

12 of 99 Swine Flu deaths have no previous diseases

Of course the sample is only 127 in USA but it should give you a good
idea if swine flu is milder than normal flu.

Interesting to note that 10% are smokers versus 11% for asthma and 7%
pregnant.


http://www.rttnews.com/Content/GeneralNews.aspx?Node=B1&Id=990060


U.S. Has One Million Swine Flu Cases Now
6/26/2009 5:14 AM ET
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A Look Back At Michael Jackson's Life
(RTTNews) - The Centers for Disease Control and Prevention (CDC) said
Thursday that one million Americans were affected by swine flu--
accounting for roughly half the world's swine flu cases--since the
epidemic broke out in southern neighbor Mexico in April, reports say.

Lyn Finelli, a flu surveillance official with the CDC, made the one
million estimate in a presentation to the vaccine panel of the U.S.
Advisory Committee on Immunization Practices in Atlanta. The number is
derived from mathematical modeling, based on surveys by health
officials.

She said half those cases were in New York City and 6% or more of some
urban areas were affected. The percentage of the cases needing
hospital treatment was growing despite the normal flu season being
over, perhaps due to closer scrutiny of very sick patients.

Regular seasonal flu affects anywhere from 15 million to 60 million
Americans each year. Other health problems have been a contributory
factor in most cases: about one in three of the hospital cases had
asthma or chronic lung disease,16% diabetes, 12% immune system
problems and 11% chronic heart disease besides 10% are current smokers
and 7% are pregnant women.

An analysis of 99 of the 127 Americans who died of swine flu shows
that 87 of them also suffered from one underlying condition or the
other: 11% had asthma, 24% other lung diseases, 13% diabetes, 11%
morbid obesity and 34% obesity.

Thursday, 25 June 2009

Exposed: Australian Experts are not even doctors

In fact doctors' views are not even considered at all in Australia.

Otherwise, what expert will conclude that Swine flu is MILDER than
Common Flu????

What is worrying is the fact exposed by this Booy person:

"But Booy warns: "I wouldn't recommend throwing influenza parties -
you might be one of the unlucky ones that gets a severe case".

About 30-50 per cent of deaths in North America were among those who
had no underlying risk factors, he says."

I must have read it earlier but gave no emphasis to it because there
is very little detail.

I managed to scan 4 previously healthy deaths only, using Google News.


It was the flu Australia had to have
KATE BENSON AND LOUISE HALL
25/06/2009 7:46:00 AM
IT has been more than five weeks since swine flu landed in Australia.
Now more than 2400 people have tested positive and three people have
died. Thousands have been quarantined, schools have been closed, and
understaffed emergency departments have struggled with an influx of
patients, suddenly highly conscious of every sniffle and cough.

Since it was first detected in Mexico in March, the World Health
Organisation says at least 52,160 people have been diagnosed and 230
have died. But the real figures will be much higher. The WHO says its
statistics are unreliable because some countries are no longer
counting and poor countries do not have the means to reliably detect
cases.

What we do know is that swine flu or the A(H1N1) virus seems to hit
younger people hardest and, that while many people who died after
contracting the virus had underlying medical conditions, some did not.

When swine flu arrived in Australia on May 9, experts predicted it
could kill up to 25,000 people, lay low up to half the workforce and
cause "massive" economic damage.

If it resembled the 1918 influenza pandemic, health bureaucrats
warned, the nation could be crippled for up to 10 months, with the
tourism industry being particularly hard hit.

More than 2 million people would be infected and millions more
affected by university, school and child-care centre closures,
transport restrictions and health system chaos.

But last week, the Federal Government downgraded Australia's swine flu
alert phase, ending mandatory quarantine, thermal imaging at airports
and compulsory testing.

The "protect" phase was created after it became clear the Government's
pandemic plan had been devised for a more virulent and deadly strain
and the tough measures were not needed for such a mild virus.

The new alert level means those with flu-like symptoms will no longer
be routinely tested. Anyone who is sick is "strongly advised" to stay
at home until their symptoms resolve. But they will not be forced into
quarantine, nor will those who have had contact with a swine flu
victim.

Those moderately sick should see a GP and those who are severely ill
should go to a hospital emergency department. Antiviral medications,
such as Tamiflu and Relenza, will not be prescribed to people
diagnosed with, or suspected of having, swine flu, unless they are at
risk of developing serious complications. Pregnant women, the morbidly
obese, people with respiratory illness and suppressed immune systems
are considered to be at risk.

Pregnant women can take antiviral medications, but Tamiflu and Relenza
are relatively new drugs and yet to be declared safe in the long term.
Those breastfeeding can take Relenza, but it will be prescribed only
if there is a high risk of complications.

Mass gatherings, such as football finals, will go ahead and schools
will not be closed, even if many children are diagnosed.

A Department of Education spokeswoman says the Board of Studies may
award substitute marks to HSC students who contract swine flu and
allow some students to complete assessment tasks at home.

But the Government's sudden change of heart has left at least one
influenza expert dubious.

Calling the decision political, Nikolai Petrovsky, of Flinders
University in Adelaide, said "doctors who look after the patients who
die from influenza each year would never label it a 'mild' infection".

"Influenza, through its ability to mutate and exchange genetic
material with related viruses, has a potential to change its nature
overnight from benign to highly lethal," Petrovsky said.

"The biggest concern of all will be when [it] becomes established in
South-East Asia and particularly Indonesia and Vietnam where avian
influenza remains a major concern. Should swine flu mix with H5N1
avian flu then all bets are off."

Research published last year showed most new flu strains had their
beginnings in northern Asia during October to March each year, moving
to North America and Europe, then Australia a few months later,
mutating constantly.

Australia's most common strain of flu, H3N2, has been circulating
annually in Australia for the past 40 years, peaking every three to
four years.

Thus swine flu is expected to return for decades, the head of clinical
research at the National Centre for Immunisation Research and
Surveillance at the University of Sydney, Robert Booy, says. "But most
people will develop some immunity to it. The problem is that
eventually it will gain an important mutation that we have no immunity
to."

Genetic similarities between pigs and humans made it easier for flu
strains to jump between the two species, with the Asian and Hong Kong
flus in1957 and 1968 both originating in pigs in China, but
Australians should not fear contracting other animal strains, Booy
says.

"Even the avian flu didn't make the cross to humans easily. You
basically had to sleep with a chicken in your bed to get it."

But Peter Collignon, a professor of microbiology and infectious
diseases at the Australian National University and a vocal opponent of
the Government's hardline measures to stop the virus, says swine flu
is proving to be less aggressive than the seasonal flu and "99 per
cent of people just get better on their own".

He says there is still no data to back up fears of a second or third
more virulent wave in the next few months and years, and most of the
deaths from the more virulent second wave of the Spanish flu in 1918
were caused by bacterial pneumonia, a secondary infection which can
now be treated with antibiotics.

Swine flu may not be the mass killer it was first feared, but there is
no doubt it has left the NSW Health Department reeling and people
confused and fearful. At times, communication between the federal and
state health departments seemed limited, answers were thin on the
ground and major mistakes were made, leaving NSW open to ridicule.

Last month, about 1800 people aboard a cruise ship were allowed to
disembark in Sydney without being tested, despite swine flu being on
board.

The ship was subsequently cleared to travel to the Whitsundays the
same night, a move which infuriated Queensland authorities, forced to
divert the ship while swabs were taken.

Another cruise ship was denied access to dock in New Caledonia because
crew members developed swine flu, but the ship did dock in Vanuatu and
Fiji.

In Sydney, some hospitals turned suspected swine flu sufferers away
because they believed they had been designated as "clean", but NSW
Health said no emergency department had been given that status.

Federal Government guidelines to avoid mass gatherings and stockpile
food and water were quickly discarded, anti-discrimination experts
warned against shunning swine flu victims and GPs complained they had
not been given enough information on dealing with suspected cases in
busy waiting rooms.

One doctor, who did not want to be named, said NSW Health's rigid
bureaucratic protocols had denied his colleagues the right to make any
decisions on testing and medication, forcing them to call the Public
Health Unit on each occasion. "GPs have had six years of university
training and an additional four to five years of postgraduate
training," the doctor said. "They have far more knowledge and
expertise than most of the federal and state bureaucrats who rule over
them with an iron fist."

Others said that antivirals were being wasted and testing was too
slow.

Lindsay Grayson and Paul Johnson, both from the infectious diseases
department of Austin Health in Melbourne, told the Medical Journal of
Australia that testing was restricted to patients who fitted the
specific case definition, and tests on all other patients who had a
clinical illness suspected of being swine flu were initially refused
or given low priority.

"This is the opposite of what should have occurred," they wrote.

Practical issues such as the adequacy of the protective mask stockpile
or the means of distributing drugs and equipment to GPs did not appear
to have been planned in detail, they said.

Roche, the manufacturer of antiviral drug Tamiflu, was forced to
suspend deliveries for two weeks for fear that the drug was being
prescribed indiscriminately by GPs, while sales of masks and anti-
bacterial handwash soared.

Flight manifests were scoured every time an international traveller
was diagnosed, but quarantine rules seemed arbitrary.

Some people were told to stay at home for seven days; others were
never told they had been in contact with the virus.

One couple left an infected cruise ship to visit a newborn grandchild
because they weren't told they had been exposed.

Anecdotal evidence of people self-quarantining abounded.

Suddenly, swine flu became the desired diagnosis for anyone wanting a
week off work.

But Booy warns: "I wouldn't recommend throwing influenza parties - you
might be one of the unlucky ones that gets a severe case".

About 30-50 per cent of deaths in North America were among those who
had no underlying risk factors, he says.

YOUR QUESTIONS ANSWERED

What are the symptoms?Swine flu resembles any other flu. Main
symptoms: sore throat, cough, runny nose, fatigue, aching muscles.

How can you tell if you have it?

You can't, except by having a doctor take a throat swab for testing.
Health authorities said last week they would no longer support testing
of anyone likely to be infected, but only those with severe disease or
risk factors such as pregnancy or asthma.

How infectious is it?

Every infected person infects an average of 1.5 others within 2 to 3
days. That is highly infectious, but on a par with other flu. Measles
and whooping cough spread much more readily.

How deadly is it?

Swine flu causes more hospitalisations than human flu. Its death rate
is about one in 1000 in developed nations - about double that of
regular flu.

Who is most likely to

be affected?

It affects healthy, young adults and children disproportionately.
Children are more at risk because they have not had previous flu
infections which may confer partial immunity. Older adults seem better
protected because they are more likely to have been exposed to flu
types similar to swine flu that circulated in the1950s.

If it's like other flu and

not exceptionally deadly,

why should we care?

Regular human flu kills 1500 to 3000 Australians annually. Depending
on how widely it spreads, swine flu could easily exceed that.
Australia is moving into the peak flu season. Hospitals may struggle
to cope.

Are there other dangers?

Swine flu in humans is a novel virus that could mutate further,
combining with other forms of flu to become more infectious, more
virulent or resistant to treatments. Because there is no vaccine,
there is still no way of holding back that worst-case scenario.

Is there any treatment?

Anti-viral medicines such as Tamiflu can prevent flu or reduce
severity and the likelihood of complications. But doctors have now
determined they should be used only for those at increased risk of
complications. Others should stay at home and use over-the-counter
medicines.

How can people avoid

catching or spreading it?

Stand a metre or more away from people with respiratory symptoms. Wash
your hands regularly; it makes a big difference. Use tissues and
dispose of them promptly. Stay away from work and keep children away
from school if you have symptoms. Support those around you, including
employees, to do this.

When will there be a vaccine?

Scientists are making rapid progress towards a vaccine, but large-
scale production will not start until late this year, at the earliest.